zileuton, a bronchodilator and leukotriene pathway inhibitor. ▪ INDICATIONS: This drug is used to treat allergic rhinitis and asthma. ▪ CONTRAINDICATIONS: Factors that prohibit the use of this drug are hepatic disease, liver function test results three times higher than upper limits, and known hypersensitivity to zileuton. ▪ ADVERSE EFFECTS: Adverse effects of this drug include dizziness, insomnia, fatigue, paresthesias, headache, nausea, abdominal pain, dyspepsia, diarrhea, liver function test abnormalities, hives, myalgia, and asthenia.
