xenobiotic /-bī·ot′ik/ [Gk, xenos, strange, bios, life] , a chemical compound foreign to a given biological system. With respect to animals and humans, xenobiotics include drugs, drug metabolites, and environmental compounds, such as pollutants that are not produced by the body. In the environment, xenobiotics include synthetic pesticides, herbicides, and industrial pollutants that would not be found in nature.