withdrawal syndrome [ME, with + drawen, to take away; Gk, syn, together, dromos, course] , a physical and mental response after cessation or severe reduction in intake of a substance such as alcohol or opiates that has been used regularly to induce euphoria, intoxication, or relief from pain or distress. The body tissues become dependent on the regular reinforcing effect of the chemical so that interruption of the dosage induces an organic mental state characterized by anxiety, restlessness, insomnia, irritability, impaired attention, and often physical illness. Also called abstinence syndrome.
