Wiskott-Aldrich syndrome /wis″ko tôl″drich/ [Alfred Wiskott, German pediatrician, 1898–1978; Robert Anderson Aldrich, American pediatrician, b. 1917] , an immunodeficiency disorder inherited as a recessive X-linked trait, characterized by thrombocytopenia, eczema, inadequate T and B cell function, and an increased susceptibility to viral, bacterial, and fungal infections and to cancer. Treatment includes the prescription of appropriate antibiotics for specific infectious organisms and the administration of transfer factor from activated lymphocytes to increase the resistance to infection and to clear the eczema. See also transfer factor.
