warfarin sodium, an oral anticoagulant. ▪ INDICATIONS: It is prescribed for the prophylaxis and treatment of thrombosis, atrial fibrillation, and embolism. ▪ CONTRAINDICATIONS: Pregnancy, severe renal or hepatic disease, uncontrolled hypertension, hemorrhage, hemorrhagic tendencies (e.g., due to hemophilia), leukemia, and known hypersensitivity to this drug are among the things that prohibit its use. ▪ ADVERSE EFFECTS: The most serious adverse effect is hemorrhage. Many other drugs interact with this drug to increase or decrease its effects.