warfarin poisoning /wôr″fərin/ [Wisconsin Alumni Research Foundation + coumarin] , a toxic condition caused by the ingestion of warfarin accidentally in the form of a rodenticide or by overdose with the substance in its pharmacologic anticoagulant form. The poison accumulates in the body and results in nosebleed, bruising, hematuria, melena, and internal hemorrhage. Vitamin K is the antidote to warfarin.