valproic acid /valprō″ik/ , an anticonvulsant. 
INDICATIONS: It is prescribed alone or in combination to treat complex partial seizures, absence seizures occurring alone or in combination with other types of seizures, mania associated with bipolar disorder, and migraine prophylaxis. CONTRAINDICATIONS: It is not recommended for use during pregnancy or lactation. Hepatic disease or dysfunction, urea cycle disorders, and known hypersensitivity to this drug prohibit its use. ADVERSE EFFECTS: Among the more severe adverse effects are decreased platelet function, hepatotoxicity, and pancreatitis. GI disturbances are common. Alopecia, rash, headache, and insomnia also may occur. A sometimes fatal hyperammonemic encephalopathy has occurred in patients with known or suspected urea cycle disorders.
