vaginal discharge, any discharge from the vagina. A clear or pearly-white discharge occurs normally. Throughout the reproductive years the amount varies greatly from woman to woman, and the amount and character vary in each woman at different times in her menstrual cycle. Before menarche and after menopause, the quantity of discharge is usually less than during the reproductive years. The discharge is largely composed of secretions of the endocervical glands. Inflammatory conditions of the vagina and cervix often cause an increase in the discharge, which may then have a foul odor and cause pruritus of the perineum and external genitalia.