triprolidine /trī·prol″idēn/ , an antihistamine. ▪ INDICATIONS: It is prescribed in the treatment of hypersensitivity reactions, including rhinitis, skin rash, and pruritus. ▪ CONTRAINDICATIONS: Asthma or known hypersensitivity to this drug prohibits its use. It is not given to newborns or lactating mothers. Adverse reactions may occur in elderly patients.