trimethadione /trī′methədī″ōn/ , an anticonvulsant. ▪ INDICATIONS: It is prescribed to prevent absence (petit mal) seizures, particularly seizures that are resistant to other therapies. ▪ CONTRAINDICATIONS: Severe renal or hepatic impairment, blood dyscrasias, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are exfoliative dermatitis, blood dyscrasias, and aplastic anemia. Sedation, diplopia, photophobia and hemeralopia (an inability to see as distinctly in bright light as in dim light) may occur.
