trifluoperazine hydrochloride /trī′flo̅o̅·ōper″əzēn/ , a phenothiazine antipsychotic. ▪ INDICATIONS: It is prescribed in the treatment of schizophrenia and other psychoses. ▪ CONTRAINDICATIONS: Concurrent administration of central nervous system depressants, coma, hepatic or renal dysfunction, severe hypotension, blood dyscrasias, or known hypersensitivity to this drug prohibits its use. It must be used with caution in patients with Parkinson’s disease. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are hypotension, hepatotoxicity, extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions.
