tolmetin sodium /tol″mətin/ , a nonsteroidal antiinflammatory agent. ▪ INDICATIONS: It is prescribed primarily in the treatment of rheumatoid arthritis, juvenile rheumatoid arthritis, and osteoarthritis. ▪ CONTRAINDICATIONS: Impaired renal function, GI disease, or known hypersensitivity to this drug, to aspirin, or to nonsteroidal antiinflammatory medications prohibits its use. Should not be used during second and third trimesters of pregnancy. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are peptic ulcer and GI distress. Dizziness, skin rash, and tinnitus commonly occur. This drug interacts with many other drugs.
