tobacco withdrawal syndrome, a change in mood or performance associated with the cessation of or reduction in exposure to nicotine. Symptoms may range from lack of concentration to anxiety and temper outbursts. A multitude of physical symptoms can also emerge. ▪ OBSERVATIONS: Symptoms associated with tobacco withdrawal can include headache, nausea, gastrointestinal disorders, fatigue, drowsiness, insomnia, and increased hunger. ▪ INTERVENTIONS: A combination of drugs and behavior-modification programs can be effective in abstaining from tobacco. ▪ PATIENT CARE CONSIDERATIONS: Many activities and events can trigger the urge to smoke. There are numerous evidenced-based strategies that can be individualized to assist a patient in remaining tobacco-free.