tizanidine, a skeletal muscle relaxant and α2-adrenergic agonist. ▪ INDICATIONS: It is used in the acute/intermittent management of increased muscle tone associated with spasticity. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Adverse effects include dry mouth, vomiting, increased ALT, abnormal liver function studies, constipation, somnolence, dizziness, speech disorder, dyskinesia, nervousness, hallucination, psychosis, urinary tract infection, blurred vision, urinary frequency, flulike syndrome, pharyngitis, and rhinitis.
