tetanus toxoid, an active immunizing agent prepared from detoxified tetanus toxin that produces an antigenic response in the body, conferring permanent immunity to tetanus infection. ▪ INDICATIONS: It is prescribed for primary active immunization against tetanus, generally in combination with diphtheria and pertussis vaccines. ▪ CONTRAINDICATIONS: Immunosuppression or immunoglobulin abnormalities, acute infection, or illness prohibits its use. ▪ ADVERSE EFFECTS: The most serious adverse effect is hypersensitivity. Pain and inflammation at the site of injection may occur.
