sulfatide lipidosis /sul″fətīd/ , an inherited lipid metabolism disorder of childhood caused by a deficiency of cerebroside sulfatase enzyme. It results in an accumulation of metachromatic lipids in tissues of the central nervous system, kidney, spleen, and other organs, leading to dementia, paralysis, and death by 10 years of age. Also called metachromatic leukodystrophy. See also lipidosis.