sodium sulfate, a saline cathartic for chronic constipation caused by peristaltic disorders. ▪ INDICATIONS: It is prescribed to achieve prompt, thorough evacuation of the bowel and, in lower dosage, for laxative effect. ▪ CONTRAINDICATIONS: Congestive heart failure, hypovolemia, or hypersensitivity to this drug prohibits its use. Frequent administration, in any dosage, is not recommended. ▪ ADVERSE EFFECTS: Among the more severe adverse effects are dehydration, hypovolemia, and electrolyte imbalance.