skullcap, an herb that is native to temperate regions of North America. ▪ INDICATIONS: It has been used as folk medicine to treat convulsions, hysteria, and nervous tension and is a common component of remedies for premenstrual syndrome and other female problems. There is insufficient reliable evidence regarding its effectiveness. ▪ CONTRAINDICATIONS: Skullcap should not be used during pregnancy and lactation, in children, or in those with known hypersensitivity to this plant.