Sister Joseph’s nodule [Sister Mary Joseph Dempsy, U.S. surgical assistant, 1856–1929] , a malignant intraabdominal neoplasm of gastric, ovarian, colorectal, or pancreatic origin and metastatic to the umbilicus. Sister Joseph, a surgical assistant and later nursing superintendent at St. Mary Hospital, Rochester, Minnesota, drew the lesion to the attention of Dr. W.J. Mayo, who published an article in 1908.