silicosis /sil′ikō″sis/ , a lung disorder caused by continued long-term inhalation of the dust of an inorganic compound, silicon dioxide, which is found in sands, quartzes, flints, and many other stones. Silicosis is characterized by the development of nodular fibrosis in the lungs. In advanced cases, severe dyspnea may develop. The incidence of silicosis is highest among industrial workers exposed to silica powder in manufacturing processes; in those who work with ceramics, sand, or stone; and in those who mine silica. Also called grinder’s disease, quartz silicosis. See also chronic obstructive pulmonary disease, inorganic dust.