sibutramine, an appetite suppressant. ▪ INDICATIONS: It is used to treat obesity in conjunction with other treatments. ▪ CONTRAINDICATIONS: The following factors prohibit its use: known hypersensitivity to this drug, hypothyroidism, anorexia nervosa, severe hepatic/renal disease, uncontrolled hypertension, cerebrovascular accident, history of coronary artery disease, congestive heart failure, arrhythmias, pregnancy, and lactation. ▪ ADVERSE EFFECTS: Tachycardia is a life-threatening effect of this drug. Other adverse effects include headache, insomnia, seizures, stimulation, drowsiness, dizziness, nervousness, emotional lability, hypotension, palpitations, vasodilation, anorexia, constipation, dry mouth, taste aberration, nausea, increased appetite, dysmenorrhea, laryngitis, pharyngitis, rhinitis, sinusitis, rash, and sweating.
