Reed-Sternberg cell

Reed-Sternberg cell [Dorothy M. Reed, American pathologist, 1874–1964; Karl Sternberg, Austrian pathologist, 1872–1935] , one of a number of large, abnormal, multinucleated reticuloendothelial cells in the lymphatic system found in Hodgkin’s disease. The number and proportion of Reed-Sternberg cells identified are the basis for the histopathological classification of Hodgkin’s disease.

Reed-Sternberg cell (Courtesy Dr. Robert W. McKenna, Department of Pathology, University of Texas Southwestern Medical School)