ranitidine /ranit″idēn/ , a histamine H2 receptor antagonist. ▪ INDICATIONS: It is prescribed in the treatment of gastroesophageal reflux disease and gastric hypersecretory conditions. ▪ CONTRAINDICATIONS: Known sensitivity to this drug prohibits its use. The drug should be used in pregnancy only if clearly needed and with caution in those with severe hepatic or renal impairment. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are acquired hemolytic anemia, agranulocytosis, atrioventricular block, agitation, dizziness, headaches, rashes, gynecomastia, and loss of libido.
