pulmonary oxygen toxicity [L, pulmoneus, lungs; Gk, toxikon, poison] , a form of oxygen poisoning caused by breathing air having an oxygen concentration of 50% or higher for 12 to 24 hours. Pathophysiological effects include pulmonary capillary endothelial damage and alveolar epithelial cell destruction. Clinical manifestations include cough, substernal pain, nausea, vomiting, and atelectasis.