propantheline bromide /-pan″thəlēn/ , an anticholinergic/antispasmodic. ▪ INDICATIONS: It is prescribed as an adjunct in peptic ulcer therapy, irritable bowel syndrome, and pancreatitis and for spasm of the ureters or urinary bladder. ▪ CONTRAINDICATIONS: Narrow-angle glaucoma, asthma, obstruction of the genitourinary or GI tract, severe ulcerative colitis, megacolon, myasthenia gravis, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are blurred vision, central nervous system effects, tachycardia, dry mouth, decreased sweating, and hypersensitivity reactions.