progesterone /prəjes″tərōn/ , a natural progestational hormone. ▪ INDICATIONS: It is used to prevent endometrial hyperplasia in nonhysterectomized, postmenopausal women who are receiving conjugated estrogen tablets; to treat dysfunctional uterine bleeding caused by hormonal imbalances; as a contraceptive in intrauterine devices; and in intravaginal gel for women using assisted reproductive technology. ▪ CONTRAINDICATIONS: Thrombophlebitis, liver dysfunction, breast cancer, undiagnosed uterine bleeding, pregnancy, previous stroke, or hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse reactions are pain at the site of injection, breast pain, dizziness, headache, fatigue, emotional lability, abdominal pain, muscle weakness, catabolic effects, and electrolyte disturbances.
