prochlorperazine /-klôrper″əzēn/ , a phenothiazine antipsychotic and antiemetic. ▪ INDICATIONS: It is prescribed in the treatment of psychotic disorders, and it may be used in the control of nausea and vomiting. ▪ CONTRAINDICATIONS: Parkinson’s disease, the concurrent administration of central nervous system depressants, liver or renal dysfunction, severe hypotension, or known hypersensitivity to any phenothiazine prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are hypotension, liver toxicity, extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions.
