procarbazine hydrochloride /prōkär″bəzēn/ , an antineoplastic. ▪ INDICATIONS: It is prescribed in the treatment of a variety of neoplasms, including Hodgkin’s disease, lymphomas, brain tumors, and lung cancer. ▪ CONTRAINDICATIONS: Bone marrow depression or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are bone marrow depression and GI disturbances, particularly nausea and vomiting.
