poikiloderma atrophicans vasculare /-dur′mə/ [Gk, poikilos, variation, derma, skin, a + trophe, not nourishment; L, vasculum, little vessel] , an abnormal skin condition characterized by hyperpigmentation or hypopigmentation, telangiectasia, and atrophy of the epidermis. It may be symmetric or patchy, localized, or widespread. It tends to be permanent.