phendimetrazine tartrate /fen′dīmet″rəsēn/ , a sympathomimetic amine used as an anorectic agent. ▪ INDICATIONS: It is prescribed to reduce appetite during the first few weeks of dieting during treatment of exogenous obesity. Its beneficial effects slowly disappear over 3 to 12 weeks. ▪ CONTRAINDICATIONS: Cardiovascular disease, hypertension, hyperthyroidism, glaucoma, nervousness, a history of drug abuse, concomitant administration of central nervous system stimulants or monoamine oxidase inhibitors, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are central nervous system stimulation, elevated blood pressure, insomnia, dry mouth, and tolerance to the drug.
