peak and trough specimens, serum samples collected to determine the level of an antibiotic or other pharmaceutic agent in the blood. Peak specimens, which represent the highest level, are generally collected ½ hour after the dose is given intravenously or 1 hour after it is given intramuscularly. Trough specimens, representing the lowest level, are generally collected approximately ½ hour before the next dose. See also peak method of dosing.
