papaverine hydrochloride /papav″ərēn/ , a smooth muscle relaxant and vasodilator. ▪ INDICATIONS: It is prescribed in the treatment of cardiovascular or visceral spasms. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use, and it must be used with caution in patients with glaucoma. It must be administered slowly because it can cause apnea and arrhythmias. Larger dosages can cause AV block. ▪ ADVERSE EFFECTS: The most serious adverse effects include jaundice, tachycardia, arrhythmias, drowsiness, headache, weakness, nausea, and vomiting.
