panitumumab, a miscellaneous antineoplastic drug. ▪ INDICATIONS: This drug is used to treat metastatic colon cancer expressing epidermal growth factor receptor. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include fatigue, ocular toxicity, peripheral edema, anorexia, mouth ulceration, abdominal pain, constipation, thrombophlebitis, pruritus, skin fissure, hypocalcemia, hypomagnesemia, antibody formation, dyspnea, pneumonitis, and wheezing. Life-threatening side effects include exfoliative dermatitis, bronchospasm, cough, hypoxia, and pulmonary fibrosis. Common side effects include nausea, diarrhea, vomiting, and rash.
