Paget’s disease

Paget’s disease /paj″əts/ [James Paget, English surgeon, 1814–1899] , a common nonmetabolic disease of bone of unknown cause, usually affecting middle-aged and elderly people and characterized by excessive bone destruction and unorganized bone repair. Also called osteitis deformans.

Paget’s disease: skull radiograph (Courtesy Ohio State University Medical Center)
Paget’s disease: enlarged skull (Moll, 1997)