orlistat, a lipase inhibitor. ▪ INDICATIONS: It is used to manage obesity. ▪ CONTRAINDICATIONS: Malabsorption syndrome, cholestasis, and known hypersensitivity to this drug prohibit its use. ▪ ADVERSE EFFECTS: Adverse effects include back pain, arthritis, myalgia, tendinitis, depression, anxiety, dizziness, headache, fatigue, nausea, vomiting, abdominal pain, infectious diarrhea, rectal pain, tooth disorder, urinary tract infection, vaginitis, menstrual irregularity, influenza, upper respiratory infection, eye-ear-nose-throat symptoms, dry skin, and rash. Common side effects include insomnia, oily spotting, flatus with discharge, fecal urgency, fatty/oily stool, oily evacuation, and fecal incontinence.
