opiate poisoning [Gk, opion, poppy juice; L, potio, drink] , toxic effects of a potent opioid, including depression of the brain centers, causing unconsciousness and a failure to breathe. Acute intoxication is characterized by euphoria, flushing, itching, and constriction of pupils, followed by reduced rate of respiration, hypotension, lowered body temperature, and abnormally slow heartbeat. Withdrawal is marked by effects generally the opposite of opiate poisoning, depending on the size of the dose and the duration of dependence.
