one-to-one care, 1. a method of organizing nursing services in an inpatient care unit in which one registered nurse assumes responsibility for all nursing care provided to one patient for the duration of one shift. The patient requiring 1:1 nursing care is a patient who is in a critical health state, is a suicidal risk, or who may be on medical equipment/devices requiring constant supervision and care. 2. physical and/or occupational therapy and/or speech rehabilitation provided by therapists, who work individually with a single patient in their homes, in schools, in assisted-living facilities, or in senior residences.