octreotide

octreotide, an antidiarrheal and hormone. ▪ INDICATIONS: The two brand names of this drug are used for different purposes. Sandostatin is used to treat acromegaly, carcinoid tumors, and vasoactive intestinal peptide tumors (VIPomas). Sandostatin LAR Depot is used for long-term maintenance of acromegaly, carcinoid tumors, and VIPomas. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Life-threatening effects include seizure, arrhythmias, congestive heart failure, hepatitis, GI bleeding, and pancreatitis. Other adverse effects are depression, anxiety, tremors, paranoia, chest pain, shortness of breath, thrombophlebitis, ischemia, hypertension, palpitations, galactorrhea, diabetes insipidus, increased liver function tests, urinary tract infection, pollakiuria, hematoma and inflammation of the injection site, bruising, rash, urticaria, and pain. Common side effects include headache, dizziness, fatigue, weakness, sinus bradycardia, conduction abnormalities, hyperglycemia, ketosis, hypothyroidism, hypoglycemia, diarrhea, nausea, abdominal pain, vomiting, flatulence, distension, constipation, and joint and muscle pain.