norgestrel /nôrjes″trəl/ , a progestin. ▪ INDICATIONS: It is prescribed alone or in combination with estrogen as a contraceptive. ▪ CONTRAINDICATIONS: Thrombophlebitis, liver dysfunction, unusual vaginal bleeding, breast cancer, or known hypersensitivity to this drug prohibits its use. The drug should be used with caution in patients with a history of depression. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are thrombophlebitis, embolism, depression, amenorrhea, dysfunctional uterine bleeding, breast changes, and masculinization of a female fetus. It should be discontinued immediately if vision changes, such as a complete or partial loss of vision or double vision, occur.
