nitrofurazone /-fyo̅o̅″rəzōn/ , a topical antibacterial drug. ▪ INDICATIONS: It is prescribed in the prophylaxis and treatment of infections in second- and third-degree burns and of the skin and mucous membranes. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the most serious adverse effects are severe allergic reactions and superinfections.