neurasthenia /no͝or′əsthē″nē·ə/ [Gk, neuron + a + sthenos, without strength] , 1. an abnormal condition that often follows depression, characterized by nervous exhaustion and a vague functional fatigue. 2. (in psychiatry) a stage in the recovery from a schizophrenic experience during which the patient is listless and apparently unable to cope with routine activities and relationships. −neurasthenic, adj.