myeloblast /mī″əlōblast′/ [Gk, myelos + blastos, germ] , earliest recognizable precursor of the granulocytic leukocytes. The cytoplasm appears light blue, scanty, and nongranular when seen in a stained blood film. The nucleus contains distinct chromatin material in strands, together with several nucleoli. In certain leukemias a marked increase in myeloblasts is observed in the marrow and in the peripheral blood. Compare megaloblast, myelocyte, normoblast. See also chronic myelogenous leukemia. −myeloblastic, adj.
