moxifloxacin, an antiinfective. ▪ INDICATIONS: It is used to treat acute bacterial sinusitis caused by Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis; acute bacterial exacerbation of chronic bronchitis from S. pneumoniae, H. influenzae, H. parainfluenzae, Klebsiella pneumoniae, Staphylococcus aureus, and M. catarrhalis; and community-acquired pneumonia from S. pneumoniae, H. influenzae, Mycoplasma pneumoniae, Chlamydia pneumoniae, and M. catarrhalis. ▪ CONTRAINDICATIONS: Known hypersensitivity to quinolones prohibits its use. ▪ ADVERSE EFFECTS: Seizures are a life-threatening effect of this drug. Other adverse effects include prolonged QT interval, dizziness, fatigue, insomnia, depression, confusion, increased ALT and AST, flatulence, heartburn, oral candidiasis, dysphagia, pruritus, urticaria, photosensitivity, flushing, fever, chills, tremor, arthralgia, and tendon rupture. Common side effects include headache, restlessness, nausea, diarrhea, and rash.
