midodrine, a vasopressor. ▪ INDICATIONS: It is used to treat orthostatic hypotension. ▪ CONTRAINDICATIONS: Factors that prohibit its use include known hypersensitivity to midodrine, severe organic heart disease, acute renal disease, urinary retention, pheochromocytoma, thyrotoxicosis, and persistent or excessive supine hypertension. ▪ ADVERSE EFFECTS: Adverse effects include drowsiness, restlessness, headache, chills, nausea, anorexia, dry mouth, blurred vision, pruritus, piloerection, rash, urinary urgency, and supine hypertension. Common side effects are paresthesia and pain.
