micafungin, a systemic antifungal drug. ▪ INDICATIONS: This drug is used in the treatment of esophageal candidiasis and susceptible candida species (Candida albicans, C. glabrata, C. krusei, C. parapsilosis, and C. tropicalis) and in prophylaxis of candida infections in patients undergoing hepatopoietic stem cell transplantation. ▪ CONTRAINDICATIONS: Known hypersensitivity to this drug or to other ecinocandins prohibits its use. ▪ ADVERSE EFFECTS: Adverse effects of this drug include dizziness, flushing, hypertension, phlebitis, abdominal pain, hypokalemia, hypocalcemia, and hypomagnesemia. Life-threatening side effects include seizures, neutropenia, thrombocytopenia, leukopenia, coagulopathy, anemia, and hemolytic anemia. Common side effects include headache; somnolence; nausea; anorexia; vomiting; diarrhea; increased aspartate aminotransferase, alanine aminotransferase, alkaline phosphate, and blood dehydrogenase; hyperbilirubinemia; rash; pruritus; injection site pain; and rigors.
