metoprolol tartrate /metop″rəlol/ , an antiadrenergic; a beta1-receptor antagonist. ▪ INDICATIONS: It is prescribed to treat hypertension and angina pectoris and to prevent myocardial infarction and atrial flutter or fibrillation. It also has proven benefits for patients with congestive heart failure when used in combination with other drugs. Unlabeled uses include migraine prophylaxis and treatment of essential tremor and ventricular arrhythmias. ▪ CONTRAINDICATIONS: Bradycardia, cardiogenic shock, overt cardiac failure, bronchospastic disease, or known hypersensitivity to this drug prohibits its use. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are fatigue, bradycardia, bronchospasms, decreased sexual ability, and GI upset.
