methocarbamol /meth′əkär″bəmol/ , a skeletal muscle relaxant. ▪ INDICATIONS: It is prescribed in the relief of skeletal muscle spasm. ▪ CONTRAINDICATIONS: Renal dysfunction, central nervous system depression, or known hypersensitivity to this drug prohibits its use. Propylthiouracil is a better choice than methimazole for thyrotoxic crisis. ▪ ADVERSE EFFECTS: Among the more serious adverse effects are hypotension and tachycardia. Drowsiness, dizziness, vertigo, and nausea may occur.