mediate /mē″dē·āt/ [L, medio, in the middle] , 1. v., to cause a change, as in stimulation by a hormone. 2. v., to settle a dispute, as in collective bargaining. 3. adj., situated between two places, things, parts, or terms. 4. n., (in psychology) an event that follows one process or event and precedes another; for example, in the process of cognition, perception follows stimulation and precedes thinking. −mediating, adj., −mediator, n.