MCAD

MCAD, an enzyme involved in degradation of medium-chain fatty acids, medium-chain acyl-CoA dehydrogenase. Deficiency of the enzyme (MCAD deficiency) is characterized by recurring episodes of hypoglycemia, vomiting, and lethargy, with urinary excretion of medium-chain dicarboxylic acids, minimal ketogenesis, and low plasma and tissue levels of carnitine.