Mayer’s reflex /mā″ərz/ [Karl Mayer, Austrian neurologist, 1862–1932] , a normal reflex elicited by grasping the ring finger and flexing it at the metacarpophalangeal joint of a person whose hand is relaxed with thumb abducted. The normal responses are adduction and apposition of the thumb. The reflex is absent in disease of the pyramidal system.